The porous Hydroxyapatite particle was developed by wet method. The synthesis condition to make the spherical and porous Hydroxyapatite was examined. To synthesized the Hydroxyapatite, phosphorus and calcium were dissolved in water and the solution was stirred. Calcium and phosphorus ratio and the concentration in eh solution have been changed. As a result, the microscopic particles generated iit in solution. The generated crystal was Hydroxyapatite. The condition of synthesising are target Hydroxyapatite has been understood. The surface area of the Hydroxyapatite whose particle diameter is 3 micros was 72m/2g. A spherical Hydroxyapatite was a set of a plate-like crystal. The particle size can be controlled by a solution and molar ratio.