To avoid the risk of cancer or respiratory diseases, nanofibres have to biograde in lung fluid when inhaled. There are two main factors affecting behaviour of the nanofibres in living tissue - geometry of fibres and biopersistance. A dissolution rate of SiO2 nanofibres in a stimulated lung environment was tested in this work. Distilled water buffered with TRIS and HCI to pH 7.6 was used as a simple stimulated extracellular lung fluid (SLF). Fibres were tested both under the static and dynamic conditions of the corrosive solution. Dissolution rates were calculated from both SiO2 concentration changes in solutions and weight changes of fibres during the exposition. The dissolution rate of tested SiO2 nanofibres was at the rate limit, where fibres could be considered as harmless for health.
