The restoration and conservation of tangible Cultural Heritage requires a multidisciplinary approach in order to develop tailored conservation strategies for cleaning and protecting precious works of art of archaeological and historical interest. The results from this paper show the feasibility of the application of low pressure plasma treatments in particular for metallic artifacts. Due to the low impact on the substrates, low pressure plasma treatments may be suggested for restoration and conservation of other typologies of artifacts such as glasses, mosaics, paintings, papers etc. Further investigations are running for optimising the cleaning procedure as a function of the chemical composition of the patina and for optimising the deposition of plasma coatings as a function of the surface condition of the artifacts.
